Psychiatry and Clinical Psychopharmacology
Case Report

Methylphenidate for the treatment of erectile dysfunction induced by long acting injectable paliperidone palmitate: a case report

1.

University Malaya, Faculty of Medicine, Department of Psychological Medicine, Kuala Lumpur - Malaysia

2.

Department of Psychological Medicine, Faculty of Medicine, University Malaya, Kuala Lumpur - Malaysia

3.

University Malaya, Faculty of Medicine, Department of Psychological Medicine, Kuala Lumpur - Malaysia

Psychiatry and Clinical Psychopharmacology 2013; 23: 361-364
DOI: 10.5455/bcp.20130308022301
Read: 797 Downloads: 478 Published: 22 February 2021

Erectile dysfunction is one of the common sexual adverse effects encountered in male patients treated with antipsychotics. It is associated with prolactin secretion secondary to dopamine antagonism by the antipsychotics. Methylphenidate is a psychostimulant that inhibits the reuptake of dopamine. In this case, we report a 42 year old schizophrenic male, who developed erectile dysfunction after administration of a long acting injectable antipsychotic, namely paliperidone palmitate. The erectile dysfunction did not respond to sildenafil but recovered with the treatment of methylphenidate 10mg. The current finding suggests that clinicians should be aware of the possible emergence of erectile dysfunction among patients on long acting injectable antipsychotics. Methylphenidate may be an alternative treatment option for erectile dysfunction induced by antipsychotics

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