Psychiatry and Clinical Psychopharmacology
Case Report

Use of Clonidine in Attention Deficit Hyperactivity Disorder and Autism Spectrum Disorder Comorbidity: Report of 3 Cases

1.

Department of Child and Adolescent Psychiatry, Ankara University, Faculty of Medicine, Ankara, Turkey

2.

Department of Child and Adolescent Psychiatry, Ankara Bilkent City Hospital, Ankara, Turkey

3.

Department of Child and Adolescent Psychiatry, Şanlıurfa Mehmet Akif İnan Training and Research Hospital, Şanlıurfa, Turkey

Psychiatry and Clinical Psychopharmacology 2023; 33: 326-329
DOI: 10.5152/pcp.2023.23690
Read: 3577 Downloads: 576 Published: 26 October 2023

Clonidine has been widely used in child and adolescent psychiatry, especially in attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD), which are recently categorized under neurodevelopmental disorders. However, it is not recommended as a first-line medication for treatment, and current data on the use of clonidine are limited. Herein, we present 3 cases with ADHD and ASD comorbidity, if any, as well as other neurodevelopmental disorders, including intellectual disability and Tourette’s disorder, treated with clonidine. At the second-month follow-up, substantial improvements were observed in subscale scores of Conners’s Parent Rating Scale–Revised Long Form, and Autism Behavior Checklist. Our case report indicated that clonidine is well tolerated, safe, and effective in improving both ADHD- and ASD-related symptoms as well as disruptive, aggressive behaviors and tics in children with multiple neurodevelopmental disorders.

Cite this article as: Temeltürk RD, İlçioğlu Ekici G, Efendi GY, Kılıç BG. Use of clonidine in attention deficit hyperactivity disorder and autism spectrum disorder comorbidity: Report of 3 cases. Psychiatry Clin Psychopharmacol. 2023;33(4):326-329.

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