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Objective: This study investigated the extent to which demographic and psychological variables may inşuence postoperative pain after breast conserving surgery.
Methods: Thirty-five patients aged 18 to 65, with an American Society of Anesthesiologist physical status I or II and body mass index between 18.42 and 42.97, undergoing breast-conserving surgery were enrolled. State trait anxiety inventory (STAI) and beck depression inventory (BDI) were used to assess patients’ psychological status one week before the operation. General anesthesia and postoperative analgesia were standardized. Patients were asked to rate their surgical site pain by Numeric Rating Scale at rest (NRSr) at 1, 2, 4 and 12 hours after surgery. Age, marital status, preoperative pain presence, neoadjuvant chemotherapy applying and educational status were noted. Pearson’ correlation and chi-square test were used for statistical analysis.
Results: There were no serious adverse events during the whole study period. Eight patients suffered from nausea and received ondansetron 4 mg as antiemetic medication. Two of these patients had vomiting. Values of hemodynamic and respiratory changes were stable in all the patients through the 24-hour postoperative period. The average age of patients was 42.91±10.25, STAI-1 43.44±10.67, STAI-2 43.91±7.15, BDI 11.91±8.49. The median NRSr points are 5, 3, 2, 1 at 1., 2., 4., and 12. hour respectively. Pearson r showed positive correlation between depression and only NRSr at postoperative 4. hour (p<0.05). Marital and educational status, neoadjuvant chemotherapy and preoperative pain were unrelated to any of the measures.
Conclusion: However, given that anxiety and depression were not significantly associated with postoperative pain in this study, there is a need for further studies with more cases.