Psychiatry and Clinical Psychopharmacology

Schizophrenia and other psychotic disorders Cerebellar agenesia and schizophrenia: a case report

Psychiatry and Clinical Psychopharmacology 2013; 23: Supplement S196-S196
Read: 569 Published: 20 March 2021

Introduction: Cerebellum, which is related to regulation of motor coordination, has shown to be related with high cortical functions as well according to latest studies. Studies focused on schizophrenia patients showed functional and structural changes in the cerebellum. In this study we presented a schizophrenia case with right cerebellar hemiatrophy.

Case: A 21-year- old male patient with known diagnosis of schizophrenia from five years and has dominant audial and visual hallucinations has showed complete right cerebellar atrophy except for right cerebellar peduncle on MRI. Anti psychotic therapy of sufficient dose and time could not lead particular improvement of symptoms. Positive and negative symptoms were improved after additional clozapine and valproate therapy to the paliperidone depot regimen.

Discussion: Cerebellar pathologies are found to be related with early started schizophrenia, positive psychotic symptoms and drug resistance. Clinicians must keep in mind the presentation with positive psychotic symptoms and drug resistance in schizophrenia cases with concomitant cerebellar pathologies.

EISSN 2475-0581