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Cognitive impairment is the most common chronic sequela of brain injury, which can result in more persistent disability than the physical injury. However, there are no medications with an approved indication for treating brain injury related cognitive impairment. The purpose of this poster is to present a case study of a patient who sustained a severe hemorrhagic brain injury and who subsequently experienced cognitive recovery to an unexpected degree. Based on all criteria, this patient's prognosis was extremely poor. Initially, he had GCS of 7/15. Upon admission to our facility for rehabilitation, 4 months after injury, he had a Rancho Los Amigos score of II, meaning that he had nonspecific non- purposeful reactions to stimuli. Despite this, he survived his brain injury in far more than a minimally responsive state and today can reasonably be assigned the highest Rancho Los Amigos score of VIII, meaning that he is able to learn new things and compensate for his problems. He exhibits more şexibility in thinking and realizes that he has a problem in his thinking and memory. The patient's remarkable recovery can be attributed to the team effort; however, in this presentation I will focus on the psychopharmacological intervention, which played a significant role in the patient's cognitive and psychological recovery.