Psychiatry and Clinical Psychopharmacology

Parkinsonism with lithium and valproic acid treatment

Psychiatry and Clinical Psychopharmacology 2014; 24: Supplement S346-S346
Read: 928 Published: 17 February 2021

Medication-induced Parkinsonism occurs frequently in patients using antipsychotic medication, but is a rare complication in patients receiving long-term treatment with mood stabilizers. A patient with the diagnosis of bipolar disorder admitted to neurology clinic due to severe Parkinsonism symptoms of rigidity, tremor and altered gait. Parkinson’s disease was the diagnosis and various anti parkinsonian medications were started. He was also consulted to psychiatry due to comorbid diagnosis of bipolar disorder. He had been treated with lithium for nine months. The Parkinsonism symptoms had been aggravated after valproic acid addition. He was hospitalized during the clinical course, anti parkinsonian drugs, lithium and valproic acid were tapered down slowly and ceased. Almost all Parkinsonism symptoms were recovered in a few weeks. As a conclusion, drug induced Parkinsonism with mood stabilizers should be considered before the diagnosis of Parkinson’s disease.

EISSN 2475-0581