Night Eating Syndrome Among Euthymic Patients With Bipolar I Disorder May Be Common and Related With Eating Concerns and Atypical Depression: A Cross-Sectional, Clinic-Based Study

Background: Current studies indicate a strong relationship between Night Eating Syndrome (NES) and obesity, while studies on Bipolar Disorder (BPD) show that patients with BPD form an important risk group in terms of obesity. The aims of this study were to investigate the frequency of NES in patients with (Bipolar Disorder Type 1) BPD1; and to determine the clinical features associated with NES.

Methods: A total of 94 euthymic patients diagnosed with BPD1 according to Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM 5) were evaluated with Sociodemographic Data Form, Structured Clinical Interview for DSM-IV (SCID-I), Young Mania Rating Scale (YMRS), Hamilton Depression Scale (HDS), Beck Anxiety Inventory, Eating Disorder Examination Questionnaire (EDE-Q), Night Eating Questionnaire (NEQ), Night Eating Syndrome Questionnaire (NESQ). The diagnosis of NES was made by clinical interview with the participants for the differential diagnosis of other eating disorders and sleep disorders. The height, weight, and waist circumference of the participants were measured. The results of all analyses were considered significant when p <0.05

Results: The incidence of NES in BPD1 was 34%. The presence of AD, atypical antipsychotic medication use, binge eating, eating concern and HDS scores were significantly higher in BPD1 patients with NES than BPD1 patients without NES (p<0.05) The presence of AD, the use of atypical antipsychotics and eating concern were found to be significant determinants of NES in BPD1 (p<0.05).

Conclusions: Our results may have implications for the choice of treatment and course of BPD1. Studies comparing normal controls and BPD1 are viewed as very promising for the conceptualization of BPD1.

To cite this article: Sema Ulukaya, Ozge Sahmelikoglu Onur, Murat Erkiran. Night Eating Syndrome Among Euthymic Patients With Bipolar I Disorder May Be Common and Related With Eating Concerns and Atypical Depression: A Cross-Sectional, Clinic-Based Study. Psychiatry and Clinical Psychopharmacology 2020;30(1):38-46