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Objective: To examine cataract formation and assess intraocular pressure (IOP) measurement with Goldmann applanation tonometry in children taking methylphenidate hydrochloride.
Methods: Forty children with attention deficit hyperactivity disorder aged 9-18 years for whom methylphenidate hydrochloride was indicated and used for at least one year were included in this study. Examinations including IOP measurement and anterior and posterior segment examination were performed.
Results: In this study we present our preliminary results. We plan to examine consecutively one hundred children. Forty patients received ophthalmic examinations. The 40 patients included 27 males, 13 females, mean age 9.6 (9-18) years; methylphenidate hydrochloride was given for attention deficit hyperactivity disorder. Mean MPH dosage was 0.9±0.10 mg/kg/day and mean duration of MPH usage was 25 months. High intraocular pressure was not measured in any of the patients in the study. Cataract formation was observed in 4 eyes of 4 patient.
Conclusion: We detect long-term use of methylphenidate hydrochloride induce cataract formation. In particular, patients using methylphenidate longer than two years should undergo regular eye examination.