Psychiatry and Clinical Psychopharmacology
Case Report

Melatonin Related Acneiform Lesions: A Case Report and Potential Mechanism

1.

Department of Psychiatry, Acıbadem Mehmet Ali Aydinlar University School of Medicine, Atakent Hospital, Istanbul, Turkey

2.

Department of Neurology, Bakirkoy Prof. Mazhar Osman Training and Research Hospital for Psychiatry, Neurology, and Neurosurgery, Istanbul, Turkey

3.

Department of Biochemistry, Marmara University School of Dentistry, Istanbul, Turkey

4.

Department of Neurology, Acıbadem Mehmet Ali Aydinlar University School of Medicine, Istanbul, Turkey

Psychiatry and Clinical Psychopharmacology 2021; 31: 241-244
DOI: 10.5152/pcp.2021.21234
Read: 1243 Downloads: 332 Published: 11 June 2021

Melatonin (MLT) is a hormone secreted by the pineal gland according to the circadian rhythm, which is generated by the suprachiasmatic nucleus. The sleep-promoting effect of exogenous MLT is used to treat sleep disorders. The most common side effects reported are headache, somnolence, palpitations, and abdominal pain. Some studies showed dermatological side effects with the use of exogenous MLT, but did not list the specific symptoms. In this article, we describe a case of facial acne occurring after the use of MLT, which is generally known to have protective and healing effects on the skin, and the potential mechanism of this surprising side effect.

Cite this article as: Sancak B, Ozdemir Z, Ozcan O, Acar E. Melatonin related acneiform lesions: A case report and potential mechanism. Psychiatr Clin Psychopharmacol. 2021; 31(2): 241-244.

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