Background: The aim of this study was to explore the influence of individualized psychological nursing on the quality of life in patients with diabetes mellitus.
Methods: A single-center cohort study with an ambispective design was conducted. According to a 1:1 ratio, the retrospective cohort included 48 patients from January 2022 to December 2022, which was the control group (CG), and the prospective cohort included 48 patients from January 2023 to December 2023, which was the intervention group (IG). The IG carried out individualized psychological intervention on the basis of routine nursing. The blood glucose control status, blood lipid metabolism indicators, negative emotions, self-management ability, and quality of life were compared between groups. The correlation between negative emotions, self-management ability, and quality of life as well as mediating effect test were analyzed.
Results: After 6 months of follow-up, the differences of fasting blood glucose (FBG), 2-hour postprandial blood glucose (2hPG), glycosylated hemoglobin (HbA1c), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol(HDL-C), and triglyceride before and after intervention in IG were higher than those in CG (P < .05). The scores of Self-rating Anxiety Scale (SAS), Self-rating Depression Scale (SDS), and Diabetes Specific Quality of Life Scale (DSQL) in IG after 6 weeks and 12 weeks of intervention and after 6 months of follow-up were lower than those in CG while the score of the Type 2 Diabetes Self-Care Scale (2DSCS) was higher than that in CG (P < .05). The SAS and SDS were positively correlated with DSQL (P < .001), and 2DSCS was negatively correlated with DSQL (P < .001). The SAS and SDS played a partial mediating role between 2DSCS and DSQL, and their mediating effects accounted for 23.08% and 18.25% of the total effects respectively.
Conclusion: Individualized psychological nursing can improve the negative emotions in patients with type 2 diabetes mellitus, and enhance self-management ability and quality of life. Negative emotions play a partial mediating role between self-management ability and quality of life.
Cite this article as: Zhang L. Influence of individualized psychological nursing on quality of life in patients with diabetes mellitus. Psychiatry Clin Psychopharmacol. Published online September 19, 2025. doi:10.5152/pcp.2025.251072.