Psychiatry and Clinical Psychopharmacology

Homocystinuria and early onset schizophrenia: a case report

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Celal Bayar Üniversitesi Tıp Fakültesi Psikiyatri AD, Manisa-Türkiye

Psychiatry and Clinical Psychopharmacology 2008; 18: 298-305
Read: 808 Downloads: 544 Published: 04 March 2021

Although schizophrenia is known as a late adolescence or early adulthood disorder psychotic symptoms can be seen in children. Schizophrenia which begins before 17-18 years of age is named as “early onset schizophrenia” and before age of 13 is named as “very early onset schizophrenia”. Studies on organic etiology of schizophrenia were increased after the description of early onset schizophrenia. It was determined that cerebral trauma, infections, demyelinization diseases, endocrinopathies, systemic diseases, vitamin deficiencies, drugs, epilepsy, sex chromosome abnormalities, and diseases with Mendelian inheritance can cause clinical symptoms like schizophrenia. In this article a homocystinuria case which was diagnosed as early onset schizophrenia according to its onset is presented.


Homosistinüri ve erken başlangıçlı şizofreni: Olgu sunumu
 

fiizofreni geç ergenlik veya erken eriflkin hastal›¤› olarak bilinmesine karfl›n psikotik belirtiler çocuklarda da gözlenebilir. 17- 18 yafl öncesi bafllayan flizofreni için “erken bafllang›çl› flizofreni”, 13 yafl öncesi bafllayanlar için ise de “çok erken bafllang›çl› flizofreni” tan›mlamalar› kullan›lmaktad›r. Erken bafllang›çl› flizofreninin tan›mlanmas›yla birlikte bu olgularda organik etiyolojiye yönelik araflt›rmalar artm›flt›r ve serebral travma, enfeksiyonlar, demiyelinizan hastal›klar, endokrin bozukluklar, sistemik hastal›klar, vitamin eksiklikleri, ilaçlar, epilepsi, seks kromozomu anormallikleri ve Mendelian geçifl gösteren hastal›klar›n flizofreni benzeri klinik tablo oluflturabilece¤i saptanm›flt›r. Bu makalede klinik belirti örüntüsü de¤erlendirildi¤inde erken bafllang›çl› flizofreni tan›s› alm›fl ancak etiyolojik araflt›rma sonucu belirtilerin homosistinüriye ba¤l› geliflti¤i anlafl›lan bir olgu sunulmaktad›r.

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EISSN 2475-0581