Psychiatry and Clinical Psychopharmacology
Original Article

Executive functions and impulsivity in suicide attempter adolescents with major depressive disorder

1.

Nevsehir State Hospital, Nevsehir, Turkey

2.

Department of Child and Adolescent Psychiatry, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey

3.

Department of Child And Adolescent Psychiatry, Dokuz Eylul University, Faculty of Medicine, Izmir-Turkey

4.

Department of Psychiatry, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey

5.

Department of Child and Adolescent Psychiatry, Izmir Katip Celebi University Faculty of Medicine, Izmir, Turkey

6.

Department of Pharmacology, Anadolu University, Faculty of Pharmacy, Eskisehir-Turkey

7.

Department of Neuroscience, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey

8.

Department of Psychology, Faculty of Arts, Dokuz Eylul University, Izmir, Turkey

Psychiatry and Clinical Psychopharmacology 2019; 29: 332-339
DOI: 10.1080/24750573.2018.1541647
Read: 946 Downloads: 506 Published: 05 February 2021

OBJECTIVE: The aim of this study was to examine the relationship between executive functions and suicidality in terms of impulsivity and depression severity.

METHODS: Depressed adolescents who have made a suicide attempt in the last year (n = 32), depressed adolescents without a suicide attempt (n = 30), and healthy controls (n = 30) participated in the study in Dokuz Eylul University Faculty of Medicine, Department of Child and Adolescent Psychiatry. Clinical diagnoses were made according to the DSM-IV by applying Kiddie Schedule for Affective Disorders and Schizophrenia Present and Lifetime Version (K-SADS-PL). Data were collected by using a sociodemographic data form, the Beck Depression Inventory (BDI), Barratt Impulsiveness Scale, and the Children’s Depression Rating Scale – Revised (CDRS-R). To evaluate all participants’ intelligence scores, the Wechsler Intelligence Scale for Children (WISC-R) was applied for adolescents aged under 16 years, and the Wechsler Adult Intelligence Scale (WAIS) was applied to adolescents aged 16–18 years. To determine the performance-based executive functions, Wisconsin Card Sorting Test and Stroop Test were applied to all participants.

RESULTS: In this study, the participants who had made a suicide attempt displayed lower performance in the Stroop Test, especially in part 1 and part 4 compared with the controls (p = .04 and p = .011). Depressive patients also exhibited lower performance in the Stroop Test in part 3 compared with the controls (p = .049). Impulsivity was found more severe in depressive patients compared with controls (p < .001). There were no statistically significant differences between depressive patients with or without suicide attempt in terms of depression severity.

CONCLUSION: Executive dysfunction appears to be associated with suicidal behaviour in adolescents with the major depressive disorder. This findings need to be replicated with a larger sample size in the future.

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EISSN 2475-0581