Psychiatry and Clinical Psychopharmacology

Evaluation of the Process of Acute Treatment for Depression in Terms of Monitoring Activity and Sleep Efficiency with Actigraphy


Department of Psychiatry, Canakkale Onsekiz Mart University School of Medicine, Canakkale, Turkey


Department of Psychiatry, Bakirkoy Training and Research Hospital for Psychiatry, Neurology and Neurosurgery, İstanbul, Turkey

Psychiatry and Clinical Psychopharmacology 2021; 31: 213-218
DOI: 10.5152/pcp.2021.21335
Read: 1019 Downloads: 88 Published: 28 June 2021

Background: This study aimed to evaluate and follow-up the process of acute treatment for depression in terms of activity and sleep efficiency using actigraphy, and thus increase the opportunities for objective measurement in the monitoring of treatment.

Methods: A total of 20 patients with depression, and 22 and age- and gender-matched healthy volunteers were included in the study. All subjects were evaluated using a sociodemographic data form, the Hamilton Depression Rating Scale (HDRS), and actigraphy for measurement of motor activity and sleep efficiency.

Results: The activity levels and sleep efficiency of the controls were significantly higher than the preand post-treatment activity levels and sleep efficiency of the patients. After the treatment process, both motor activity and sleep efficiency were found to be significantly increased in the patients. A highly significant negative correlation was found between the HDRS scores and average activity counts for active intervals (r = −0.779, P < .001), and between the HDRS scores and sleep efficiency (r = −0.616, P < .001). On the other hand, a significant negative effect was found between depression and average activity counts for active intervals (RR:0.880; 95% CI:0.782-0.991).

Conclusions: Actigraphy is a useful technique for quantifying physical activities and sleep efficiency in depressed patients. Furthermore, it may provide objective follow-up data in assessing the effects of treatment for depression.

Cite this article as: Akıncı E, İnce B. Evaluation of the process of acute treatment for depression in terms of monitoring activity and sleep efficiency with actigraphy. Psychiatr Clin Psychopharmacol. 2021; 31(2): 213-218.

EISSN 2475-0581