Psychiatry and Clinical Psychopharmacology
Original Article

Establishing the cut-off scores for the severity ranges of schizophrenia on the BPRS-6 scale: findings from the REAP-AP


Department of Psychiatry, Inje University School of Medicine, Haeundae Paik Hospital, Pusan, Republic of Korea


Department of Counselling Psychology, Honam University College of Humanities and Social Sciences, Gwangju, Republic of Korea


Department of Psychiatry, Veteran Health Service Medical Center, Seoul, Republic of Korea


Department of Psychiatry, Hanyang University Guri Hospital, Guri, Republic of Korea


Department of Psychiatry, Burdwn Medical College, Bardhaman (E), India


Institute of Mental Health and Neurosciences, Government Medical College, Srinagar, India


Department of Psychiatry, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia


Department of Neuropsychiatry, Graduate School of Medicine, Kyushu University, Fukuoka, Japan


Tunku Abdul Rahman Institute of Neuroscience, Kuala Lumpur Hospital, Kuala Lumpur, Malaysia


Department of Pharmacology, National University Hospital, Singapore, Singapore


Pakistan Psychiatric Research Centre, Lahore, Pakistan


Association for the Improvement of Mental Health Programmes, Geneva, Switzerland


Department of Social Welfare, School of Human Sciences, Seinan Gakuin University, Fukuoka, Japan

Psychiatry and Clinical Psychopharmacology 2019; 29: 895-898
DOI: 10.1080/24750573.2019.1695994
Read: 1026 Downloads: 574 Published: 08 February 2021

Objective: Using data from the Research on Asian Psychotropic Prescription Patterns for Antipsychotics (REAP-AP), our study aimed to establish the remission and severity ranges (mild, moderate, and severe) of schizophrenia on the Brief Psychiatric Rating Scale-6 (BPRS-6).

Methods: A total of 1,438 patients with schizophrenia from India, Indonesia, Japan, Malaysia, and Taiwan were enrolled in the study. Using the receiver operating characteristic (ROC) curve analyses, the optimal cut-off scores for the remission and severity ranges on the BPRS6 were established.

Results: The scalability of the BPRS-6 was considered to have an acceptable “unidimensionality” (coefficient of scalability = 0.43). The cut-off scores for the remission of schizophrenia and mild, moderate, and severe schizophrenia can be optimally defined as the BPRS-6 total score of 20, respectively.

Conclusion: The BPRS-6 can be a promising, brief, and unidimensional rating scale to supplement the measurement-based care of schizophrenia.

EISSN 2475-0581