Psychiatry and Clinical Psychopharmacology

Effectiveness and adverse effects of methylphenidate treatment in children diagnosed with disruptive mood dysregulation disorder and attention-deficit hyperactivity disorder: a preliminary report


Department of Child and Adolescent Psychiatry, Nevsehir State Hospital, Nevsehir, Turkey


Department of Child and Adolescent Psychiatry, School of Medicine, Dokuz Eylul University, Izmir, Turkey


Department of Child And Adolescent Psychiatry, Dokuz Eylul University, Faculty of Medicine, Izmir-Turkey

Psychiatry and Clinical Psychopharmacology 2017; 27: 99-100
DOI: 10.1080/24750573.2017.1293252
Read: 800 Downloads: 484 Published: 10 February 2021

Objective: Comorbidity with attention deficit hyperactivity disorder (ADHD) and disruptive mood dysregulation disorders (DMDD) is very common in children and adolescents In this study, we aimed to present a retrospective study of methylphenidate (MPH) treatment in 12 cases who were diagnosed with DMDD and ADHD.

Method: All patients were followed-up in our outpatient clinic and the effectiveness and side effects of MPH were explored. Mood Symptom Questionnaire (MSQ-7) and Clinical Global Impression-Severity (CGI-S) were used for assessing the mood symptoms and their severity.

Results: The differences between initiation time and the end-point time in CGI-S and MSQ-7 scores were statistically significant.

Conclusion: In this present study, the usage of MPH was found to lead to an increase in irritability in children with ADHD and DMDD evidently

EISSN 2475-0581