Psychiatry and Clinical Psychopharmacology

Demographic and clinical variables among mood disorders inpatients: a preliminary report

1.

Adnan Menderes Üniversitesi Tıp Fakültesi Psikiyatri AD, Ayd›n-Türkiye

Psychiatry and Clinical Psychopharmacology 2008; 18: 183-188
Read: 767 Downloads: 535 Published: 04 March 2021

Objective: There is limited data to demonstrate the clinical characteristics and variables of psychiatric inpatients in our country.The aim of this preliminary study is to investigate sociodemograph›c and cl›n›cal var›ables of inpatients, who were followed up at a mood disorders unit during a two year period. ‹n addition, patients with depressive disorders and bipolar disorders were compared in terms of these characteristics. Method: A total of 36 inpatients were evaluated in the Mood disorder unit of Psychiatry Department of Adnan Menderes University between 16.09.2004 and 01.09.2006. Diagnoses were made according to DSM-IVTR. Depressive disorders group included patients with either major depressive or recurrent depressive disorders, while bipolar disorders group consisted of patients with bipolar I, and II disorders, schizoaffective disorder-bipolar type, cyclothymic disorder and antidepressant induced mania. Results: There were 36 inpatients in total, 26 in bipolar disorders group and 10 in depressive disorders group. Age at onset was 27.7 ± 1.7 years in bipolar disorders group and 35.3 ±4.4 years in depressive disorders group. Psychosocial stress prior to the first episode was a factor in 90% of patients with depressive disorders and in 64% of patients with bipolar disorders. Family history was positive for 66.7% of patients with depressive disorders and for 57.7% of patients with bipolar disorders. History of suicide attempts was frequent in both groups; 66.7% in depressive disorders group and 70% in bipolar disorders group. Any comorbid disorder listed at axis III was present in 40% of patients in depressive disorders group and in 52% of patients in bipolar disorders group. The mean hospitalization period was 36.6±5.9 days in depressive disorders group and 40.8±5.0 days in bipolar disorders group. The use of tricyclic antidepressants were more prevalent in the depressive group, whereas the mood stabilizers and antipsychotics were dominantly preferred in the bipolar group. Discussion: The importance of epidemiologic research is increasing in our country as well as other countries recently. Valid and reliable data for bipolar disorders and other psychiatric disorders are required in Turkey. Evaluating the results of studies performed in different regions of our country will contribute to obtain the specific characteristics of psychiatric disorders in Turkey. In the study, the age of onset was earlier in the bipolar group, whereas the existance of a stressor in the first episode was more frequent in the depressive group.


Duygudurum bozukluğu tanısı ile yatan hastaların sosyodemograŞk ve klinik özellikleri: Bir ön bildirim

Amaç: Ülkemizde psikiyatrik yatan hastalar›n klinik özellik ve de¤iflkenleri hakk›ndaki az miktarda veri bulunmaktad›r. Bu ön çal›flman›n amac› iki y›ll›k bir dönemde duygudurum bozukluklar› biriminde yat›r›larak izlenen hastalar›n sosyodemografik ve klinik özelliklerini araflt›rmakt›r. Bu çal›flmada ayn› zamanda depresif bozukluk ve bipolar bozukluk bulunan hastalar›n bu özellikler yönünden karfl›laflt›r›lmas› amaçland›. Yöntem: Bu çal›flmada Adnan Menderes Üniversitesi T›p Fakültesi Hastanesinin Psikiyatri Klini¤i Duygudurum Birimi’nde 16.09.2004-01.09.2006 tarihleri aras›nda yatan 36 hasta de¤erlendirmeye al›nm›flt›r. Tan›lar DSMIV-TR s›n›fland›rmas›na göre konulmufltur. Majör depresif bozukluk ve yineleyici depresif bozukluk depresif bozukluklar; bipolar I ve II bozukluk, flizoaffektif bozukluk-bipolar tip, siklotimik bozukluk ve antidepresan ile ç›- kan mani ise bipolar bozukluklar olarak iki grup halinde de¤erlendirilmifllerdir. Bulgular: Bipolar bozukluk tan›l› 26 ve depresif bozukluk tan›l› 10 hasta olmak üzere toplam 36 hasta iki y›ll›k dönemde klinikteki ilk yat›fllar› göz önüne al›narak çal›flmaya al›nm›fllard›r. ‹lk ata¤›n bafllang›ç yafl› bipolar bozukluk grubunda 27.7±1.7 y›l, depresif bozukluk grubunda 35.3±4.4 y›l olarak bulunmufltur. Depresif bozukluk grubundaki hastalar›n %90’›nda ilk atakta stres etkeni bulunmuflken bu oran bipolar bozukluk grubundaki hastalarda %64 olarak bulunmufltur. Depresif bozuklu¤u olan hastalar›n %66.7’sinde, bipolar bozuklu¤u olan hastalar›n ise %57.7’sinde aile öyküsünde psikiyatrik bozukluk varl›¤› saptanm›flt›r. Geçmiflte intihar giriflimi her iki grupta da s›k olarak, depresif bozukluk grubunda %66.7, bipolar bozukluk grubunda %70 oranlar›nda bulunmufltur. Depresif bozukluk grubunda %40; bipolar bozukluk grubunda %52 oran›nda eksen III tan›s› saptanm›flt›r. Ortalama yat›fl süresi depresif bozukluk grubun da 36.6±5.9 gün, bipolar bozukluk grubunda 40.8±5.0 gün olarak saptanm›flt›r. Depresif bozukluk grubunda trisiklik antidepresanlar en fazla tercih edilen psikotrop iken, bipolar bozukluk grubunda duygudurum düzenleyici ve antipsikotikler daha fazla tercih edilmifltir. Tart›flma: Epidemiyolojik araflt›rmalar›n tüm dünyada oldu¤u gibi ülkemizde de önemi artmaktad›r. Türkiye’ye ait bipolar bozukluk ve di¤er psikiyatrik hastal›klara ait sa¤l›kl› ve güvenilir bilgilere gereksinim duyulmaktad›r. Ülkemizin de¤iflik bölgelerinde yap›lan çal›flma sonuçlar›n›n de¤erlendirilerek psikiyatrik hastal›klar›n Türkiye profilinin oluflturulmas›, topluma özgü özelliklerinin tan›nmas›na, risk etmenlerinin saptanmas›na, toplumsal ve demografik iliflkilerin ortaya ç›kar›lmas›na katk›da bulunacakt›r. Bu çal›flmada ilk atak bafllang›ç yafl› bipolar bozukluklu hasta grubunda daha erken bulunurken, ilk atakta stres etkeninin varl›¤› depresif bozukluk grubunda daha fazlad›r.

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