Objective: Low psychological profile in polycystic ovary syndrome (PCOS) reduces the quality of life. Considering the diagnostic criteria for PCOS, comes to the forefront in three phenotyping as classic, ovulatory and normoandrogenic. The aim of this study was to compare quality of life, depression and anxiety levels between PCOS phenotypes and a control group.
Method: One hundred and six patients and control subjects under current examination in Gulhane Military Medical Faculty, obstetrics and gynecology outpatient clinic were included in the study. PCOS patients were divided into 3 groups according to their phenotypes as classic (n = 27), ovulatory (n= 27), normoandrogenic (n= 27). The control subjects (n= 27) took part in the fourth group. Quality of life, depression, and anxiety levels were evaluated by quality of life scale for polycystic ovary syndrome, Beck Depression Inventory and Beck Anxiety Inventory respectively.
Results: Normoandrojenik phenotype was less affected than the others in terms of depression and quality of life scores. There was no difference in quality of life subscales for hirsutism, over weight and ovulatory dysfunction between PCOS phenotypes. Emotional impairment occurred most at classic phenotype. Normoandrogenic phenotype becamedistinguished from the other two phenotypes in the subscale of infertility.
Conclusion: Determination of mood changes and the associations between these changes and PCOS symptoms are considered to be a positive contribution to the improvement of symptoms in PCOS. Assessment of the impact of symptoms on phenotypes of PCOS will facilitate the management of treatment.