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Objective: Cardiac Syndrome X is defined as a condition characterized by repetitive angina-like chest pain, normal coronary arteries in angiography and positive cardiac stress test. The exact prevalence of CSX is unknown in the community but approximately 10-30% of patients undergoing coronary angiography to evaluate angina-like chest pain have normal coronary arteries. CSX is more common in women than man. The pathogenesis of CSX remains uncertain but recent findings have suggested that microvascular dysfunction, insulin resistance, abnormal cardiac sensitivity, psychological disorders may play a pathogenetic role in CSX. The aim of this study was to evaluate psychiatric comorbidity, and effect of the psychiatric support in the quality of life symptom dimension, severity and risk factors of facilitate to depression in OCD
Method: Fifty-six patients with cardiac syndrome X (CSX) and fifty-three coronary heart disease patient (CAD) were included to study. All patients were diagnosed by using the Structured Clinical Interview for DSM-IV after angiography. Health related quality of life was measured by the Short Form-36(SF-36). Beck Anxiety Scale and Beck Depression Scale were used to rate anxiety and depression severity. All scales were performed after three months.
Results: There were no significant differences in age, marital status, profession, medical and family history, and social support between two groups. In the first evaluation, anxiety and depression scores were significantly higher in CSX groups. After three months, depression scores decreased significantly in the CSX group. Physical and social functioning, role limitations (physical problems)and vitality scores were significantly higher in CSX group after the treatment. The most common comorbid psychiatric disorders were mood disorder, anxiety disorder and somatoform disorder in CSX group.
Conclusion: We found that psychiatric support improved the quality of life and reduced the chest pain in CSX patients.