Psychiatry and Clinical Psychopharmacology

Clinical psychiatry Gender difference in response to repetitive transcranial magnetic stimulation (rTMS) in patients with depression

Psychiatry and Clinical Psychopharmacology 2013; 23: Supplement S281-S282
Read: 490 Published: 17 March 2021

Objective: The relationship between sex and the psychiatric treatments were investigated for many years. Although plasma concentration of some antidepressants such as TCAs differs in gender, its clinical effects are not understood. Moreover women need less dose of antipsychotics than man for an eligible response. There are contradictory results regarding the response to rTMS according between genders.

Methods: Response to rTMS treatment of 26 females and 21 males, who were diagnosed to have depression in a university hospital according to DSM IV-R. Hamilton depression scale (HAM-D) scores were obtained before and after the treatment.

Results: Sociodemographic data were similar between the genders. While endogenous propersities were common in women (61%, n=16), reactive properties were comman in men (62%, n=14). Relapse rates and disease durations were similar between genders. HAM-D scores were significantly improved in both groups (p<0.05). However, genders were similar in terms of response such as complete remission, partial improvement and lack of response (p>0.05).

Conclusion: The relationship between genders and response to psychiatric treatment were investigated and tried to be elucidated whether it is a determining factor for response to treatment. However there is no enough data regarding rTMS treatment. Although our results indicate similar results between genders, more comprehensive studies are necessary.
 

EISSN 2475-0581