Psychiatry and Clinical Psychopharmacology
Case Report

Can Visual Hallucinations be Among the Neuropsychological Manifestations of Systemic Mastocytosis?: A Geriatric Case


Koc University Hospital, Department of Psychiatry, Istanbul


Koc University School of Medicine, Istanbul


Koc University Hospital, Department of Internal Medicine, Istanbul


Acibadem Maslak Hospital, Department of Haematology, Istanbul, Turkey

Psychiatry and Clinical Psychopharmacology 2020; 30: 324-326
DOI: 10.5455/PCP.20200316094036
Read: 968 Downloads: 526 Published: 20 January 2021

Mast cells are considered sensors of environmental and emotional stress, exist in all body parts and are related to the pathway from stress to inflammation. Mastocytosis defines a rare disease characterized by the accumulation of abnormal mast cells in multiple organs. Here, we present a 77-year-old woman with a background of aggressive systemic mastocytosis who developed impaired cognition, depression, anxiety, visual hallucinations, delusions, and insomnia. Symptoms alleviated only after initiating midostaurin, a tyrosine kinase inhibitor. Systemic mastocytosis should be kept in mind when visual hallucinations are concomitant with chronic or recurrent multi-system disturbances and do not benefit from treatment as usual.

To cite this article: Kilic O, Yilmaz UE, Komesli Z, Ercan AC, Cetiner M. Can visual hallucinations be among the neuropsychological manifestations of systemic mastocytosis?: A Geriatric Case. Psychiatry and Clinical Psychopharmacology 2020;30(3):324-326

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